crocin and depression
Crocin, the main active saffron constituent, as an adjunctive
treatment in major depressive disorder
Krocina tablet contains “crocin”; which is a natural drug carotenoid chemical compound that is responsible for the color of saffron. It is the main active constituent and antioxidant in saffron stigmas. Thus, the saffron health benefits and medicinal properties are attributed to this component. Crocin, as a medicinal supplement, is a mood enhancer with antidepressant properties. Therapeutic effects of crocin on depression, anxiety and general health were demonstrated in a clinical trial. It has also been shown to have an antiproliferative action against cancer cells, anti-alzheimer and neuroprotective effects, aphrodisiac properties against sexual dysfunction, therapeutic effects against eye disorders such as age-related macular degeneration and retinal protection in diabetic patients, hypoglycemic effects. As a powerful antioxidant, crocin showed beneficial properties in metabolic syndrome. Preliminary research in Mashhad University of Medical Sciences demonstrated the efficacy of crocin in burning mouth syndrome (BMS) which is an idiopathic condition characterized by a continuous burning sensation of the mucosa of the mouth, typically involving the tongue, with or without extension to the lips and oral mucosa.